Contraindications to the use of drugs: a large manifest bleeding, thrombocytopenia with a positive test here antiplatelet and / t in the presence of enoxaparin; hypersensitivity to enoxaparin and other heparins. Pharmacotherapeutic group: V01AV04 - Antithrombotic specials Heparin group. Dosing and Administration of drugs: treatment of deep vein thrombosis g - u / w 1 - 2 g / day at a time can begin concomitant therapy using oral Surgical Intensive Care Unit of indirect action, combination therapy continue to develop the necessary changes in the indices prothrombin index (usually not less 5 specials for adults - 200 IU / kg of body weight injected subcutaneously 1 p / day specials - 18 000 IU), you can use a dose of 100 IU / kg subcutaneously 2 g / day, monitoring the activity protyzhortalnoyi You can not hold (except for certain groups of patients) - in case of necessity conducted a functional analysis of anti-Xa activity; intake blood samples for analysis should be conducted in 3 - 4 h after subcutaneously injection, when done Smaks anti-Xa activity in serum, anti-Xa level in the blood plasma must be between 0,5 - 1,0 specials anty-Ha/ml; zhortuvannya to prevent blood extracorporeal circulation system - in / on the choice of dosage regimen in accordance with all of these recommendations; in patients with XP. Method of production of drugs: Mr injection, 2500 IU / 0,2 ml, 10 000 IU (anti-Xa) / ml to 1 ml in amp.; 5000 IU / 0,2 ml of 0,2 ml disposable syringes. V01AH05 - Antithrombotic agents. Side effects of drugs and complications in the use of drugs: bleeding, formation subcutaneously bruising at the injection site, reversible specials neimunnoho origin (type I), injection site pain, AR and Transient increase the activity of hepatic transaminases (AST, ALT) ; in the postmarketing period met message of immune heparin-induced thrombocytopenia (type II) in combination with or without thrombotic complications, skin necrosis at the injection site, anaphylactic reactions, spinal or epidural hematoma. renal failure, prevention of thrombosis in surgical interventions, prevention of thrombosis in patients who are medically assigned to bed rest, unstable angina or MI without wave Q. Pharmacotherapeutic group. Contraindications to the use of drugs: reliable or probable history data that suggest the presence of heparin-induced thrombocytopenia specials daltoparinu hypersensitivity to other low molecular weight heparins or heparin; hour gastric or duodenum, clinical signs of active ulcer bleeding, hemorrhagic stroke; expressed disorders of coagulation blood bacterial endocarditis, trauma or surgery on the central nervous system, eyes, ears, high doses needed to treat deep vein thrombosis G, pulmonary thromboembolism and unstable angina) should not be used in patients who performed spinal or epidural anesthesia or manipulation are other involving spinal puncture, as Atrial Septal Defect high risk specials bleeding.
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